Applied Therapeutics: THE CLINICAL USE OF DRUGS. Ninth Edition. Edited By. Mary Anne Koda-Kimble, PharmD. Professor of Clinical. [et al.]. p. ; cm. Applied therapeutics Rev. ed. of: Applied therapeutics: the clinical use of drugs /edited by Mary Anne Koda-Kimble [et al.]. 9th ed. c OCLC Number: Notes: Revised edition of: Applied therapeutics: the clinical use of drugs / edited by Mary Anne Koda-Kimble [and others]. 9th ed.
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Veja grátis o arquivo Applied Therapeutics, Koda Kimble 10th ed enviado para a disciplina de Farmacologia Aplicada Categoria: Outros 9th ed. c "This edition again succeeds in offering a comprehensive, updated reference covering over different disease states. Pharmacotherapy is outlined in a format. Now available in both mobile and print formats, this updated Ninth Edition provides in-depth information on the latest drug treatments for more than 85 diseases.
Opponents also contend that it lacks valid scientific evidence for claims of efficacy . However, there is survey-based research that suggests there is a correlation between attendance and alcohol sobriety .
Different results have been reached for other drugs, with the twelve steps being less beneficial for addicts to illicit substances, and least beneficial to those addicted to the physiologically and psychologically addicting opioids , for which maintenance therapies are the gold standard of care.
It gives importance to the human agency in overcoming addiction and focuses on self-empowerment and self-reliance.
It does not involve a lifetime membership concept, but people can opt to attend meetings, and choose not to after gaining recovery. This is considered to be similar to other self-help groups who work within mutual aid concepts. Rogers believed the presence of these three items, in the therapeutic relationship , could help an individual overcome any troublesome issue, including but not limited to alcohol abuse. To this end, a study  compared the relative effectiveness of three different psychotherapies in treating alcoholics who had been committed to a state hospital for sixty days: a therapy based on two-factor learning theory, client-centered therapy , and psychoanalytic therapy.
Though the authors expected the two-factor theory to be the most effective, it actually proved to be deleterious in the outcome. Surprisingly, client-centered therapy proved most effective.
It has been argued, however, these findings may be attributable to the profound difference in therapist outlook between the two-factor and client-centered approaches, rather than to client-centered techniques. A variation of Rogers' approach has been developed in which clients are directly responsible for determining the goals and objectives of the treatment. This orientation suggests the main cause of the addiction syndrome is the unconscious need to entertain and to enact various kinds of homosexual and perverse fantasies, and at the same time to avoid taking responsibility for this.
It is hypothesized specific drugs facilitate specific fantasies and using drugs is considered to be a displacement from, and a concomitant of, the compulsion to masturbate while entertaining homosexual and perverse fantasies.
The addiction syndrome is also hypothesized to be associated with life trajectories that have occurred within the context of teratogenic processes, the phases of which include social, cultural and political factors, encapsulation, traumatophobia, and masturbation as a form of self-soothing.
Additionally, homosexual content is not implicated as a necessary feature in addiction. Relapse prevention[ edit ] An influential cognitive-behavioral approach to addiction recovery and therapy has been Alan Marlatt's Relapse Prevention approach.
Self-efficacy refers to one's ability to deal competently and effectively with high-risk, relapse-provoking situations. Outcome expectancy refer to an individual's expectations about the psychoactive effects of an addictive substance. Attributions of causality refer to an individual's pattern of beliefs that relapse to drug use is a result of internal, or rather external, transient causes e. Finally, decision-making processes are implicated in the relapse process as well.
Substance use is the result of multiple decisions whose collective effects result in a consumption of the intoxicant. Furthermore, Marlatt stresses some decisions—referred to as apparently irrelevant decisions—may seem inconsequential to relapse, but may actually have downstream implications that place the user in a high-risk situation.
This will result in the creation of a high-risk situation when he realizes he is inadvertently driving by his old favorite bar. If this individual is able to employ successful coping strategies , such as distracting himself from his cravings by turning on his favorite music, then he will avoid the relapse risk PATH 1 and heighten his efficacy for future abstinence. If, however, he lacks coping mechanisms—for instance, he may begin ruminating on his cravings PATH 2 —then his efficacy for abstinence will decrease, his expectations of positive outcomes will increase, and he may experience a lapse—an isolated return to substance intoxication.
So doing results in what Marlatt refers to as the Abstinence Violation Effect, characterized by guilt for having gotten intoxicated and low efficacy for future abstinence in similar tempting situations.
This is a dangerous pathway, Marlatt proposes, to full-blown relapse. Cognitive therapy[ edit ] An additional cognitively-based model of substance abuse recovery has been offered by Aaron Beck , the father of cognitive therapy and championed in his book Cognitive Therapy of Substance Abuse.
These core beliefs, such as "I am undesirable," activate a system of addictive beliefs that result in imagined anticipatory benefits of substance use and, consequentially, craving.
Once craving has been activated, permissive beliefs "I can handle getting high just this one more time" are facilitated. Once a permissive set of beliefs have been activated, then the individual will activate drug-seeking and drug-ingesting behaviors.
The cognitive therapist's job is to uncover this underlying system of beliefs, analyze it with the patient, and thereby demonstrate its dysfunctional. The authors, editors, and publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accordance with current recommendations and practice at the time of publication.
However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new or infrequently employed drug.
Some drugs and medical devices presented in the publication have Food and Drug Administration FDA clearance for limited use in restricted research settings. It is the responsibility of the health care provider to ascertain the FDA status of each drug or device planned for use in their clinical practice.
To download additional copies of this book, call our customer service department at or fax orders to International customers should call They are truly educational visionaries whom we deeply respect as the innovators and pioneers in the teach- ing of patient-centered drug therapeutics. Their passion has touched the lives of countless health care professional students, clinicians, and patients throughout the world. The landscape of health care has evolved radically during this time, much of it spurred by remarkable advancements in drug discovery and clin- ical therapeutics.
Our authors present more than patient cases that stimulate the reader to integrate and apply therapeutic principles in the context of spe- cific clinical situations. Students and practitioners are provided with a glimpse into the minds of clinicians as they assess and solve therapeutic problems toward the development of their own critical-thinking and problem-solving skills.
Every chapter in this edition has been revised and updated to reflect our ever-changing knowledge of drugs and the application of this knowledge to the individualized therapy of patients. Additionally, content within several sections has been extensively reorganized, with new chap- ters introduced to expand important topics. Readers familiar with past editions of the text will notice some welcome changes in the tenth edition.